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Heracleum spp

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  • Common name? Toxin? Effects? Treatment?

  • Cow Parsnip, notable Heracleum Maximum in North America
  • Furanocumarins: Angelicin (upper) and Psoralen (lower); note there are other isomers not shown
  • Phototoxic vesicicular rash that form after exposed to sunlight. They intercalate with DNA leading to decreased robustness of DNA damage repair from UV sunlight.
  • Treatment: supportive, wound care.

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